🔹 About This Episode:
IIn this episode of the Longevity Podcast, Nat Niddam is joined by Chris Rhodes, nutritional biochemist and CEO of Mimio Health, to reveal the cutting-edge science of fasting mimetics—molecules that mimic the effects of fasting without actually fasting. Chris shares the story behind discovering four key metabolites our bodies naturally produce during extended fasts, and how Mimio has harnessed them into a supplement that activates key longevity pathways like AMPK, mTOR, NAD+, and sirtuins. If you’ve ever struggled with fasting but still want its cellular repair and energy-boosting benefits, this episode is a must-listen.
You’ll also learn who should not fast, how these mimetics can support aging populations, athletes, and those with metabolic challenges, and how this research may soon lead to innovations like “exercise in a pill.” Whether you’re into biohacking, optimizing for energy and brain health, or just want an easier way to support long-term wellness, this conversation will change how you think about fasting and cellular regeneration.
Listeners of this podcast can visit mimiohealth.com/nat and use code NAT FOR 20% off your first single purchase or subscription order.
🔹 What We Discuss:
Meet Chris Rhodes and his biomimetic research journey … 00:05:18
Unlocking fasting benefits without prolonged fasting … 00:09:10
Supplements vs. pharmaceuticals for longevity … 00:10:53
Fasting protocols, timing, and metabolic switching … 00:15:23
Risks of fasting, evolutionary adaptation, and muscle/bone loss … 00:18:34
Ketones, brain energy, and cognitive adaptation … 00:22:48
How fasting activates longevity and repair pathways … 00:26:23
Key cellular pathways: AMPK, mTOR, NAD, sirtuins … 00:28:04
Mimio research: discovering and testing fasting metabolites … 00:33:35
The four main fasting mimetic molecules explained … 00:42:04
Practical benefits: who should use fasting mimetics & safety … 00:59:00
Mimio in use: hunger control, GLP-1 support, and older adults … 01:03:37
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🔹 Learn More From Chris Rhodes below:
Website: http://mimiohealth.com/nat
Instagram: https://www.instagram.com/mimiohealth/
YouTube: https://www.youtube.com/@mimiohealth
Facebook: https://www.facebook.com/mimiohealth
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🔹 Find more from Nathalie:
• YouTube: / @nathalieniddam9630
• Join Nat’s Membership Community: https://www.natniddam.com/the-longevity-community
• Sign up for Nats Newsletter: https://landing.mailerlite.com/webfor…
• Instagram: / nathalieniddam
• Website: NatNiddam.com
• Facebook Group: / biohackingsuperhumanperformance
#longevitypodcast #FastingMimetics #Biohacking #AntiAging #IntermittentFasting
#ChrisRhodes #MimioHealth #CellularHealth #FastingHacks
